Catalogue Number
CT257
Description
mAb anti-human IL-12/23p40 (B-P24) - 0.5 mg
Price
€ 280.00
Characteristics
clone B-P24
Summary
The monoclonal antibody to human IL-12/23p40 (clone B-P24) recognizes the p40 subunit. The B-P24 antibody can be succesfully used in ELISA (Hessie C. et al. 2000), neutralization assays (Nagai T. et al. 2003) and in immunohistochemistry (Yawalkar N. et al. 2000).
References list
- Gram-positive bacteria are potent inducers of monocytic interleukin-12 (IL-12) while gram-negative bacteria preferentially stimulate IL-10 production.
- Timing of IFN-beta exposure during human dendritic cell maturation and naive Th cell stimulation has contrasting effects on Th1 subset generation: a role for IFN-beta-mediated regulation of IL-12 family cytokines and IL-18 in naive Th cell differentiation.
- Down-regulation of IL-12 by topical corticosteroids in chronic atopic dermatitis.