Catalogue Number
CT161
Description
mAb anti-monkey CD3 (clone FN-18) - 0.5 mg
Price
€380.00
Characteristics
clone FN-18
Summary
The monoclonal antibody to monkey CD3 (clone FN-18) was first described in 1986. The FN-18 antibody can be used in immunohistochemical staining of frozen tissues (Jonker M. et al. 2013), flow cytometric analysis (Frost P.A. et al. 2004) and intracellular staining (Aurisicchio L. et al. 2007). Further, the antibody is able to stimulate rhesus macaque PBMC (Kim J.S. et al. 2009). The FN-18 antibody has been reported to cross react with rhesus macaque, cynomolgus monkey and baboon CD3 (Nooij F.J.M. et al. 1986, Stittelaar K.J. et al. 2001 and Frost P.A. et al. 2004). Other available formats: biotin labeled (cat. no. CT162), FITC labeled (cat. no. CT163) and Cy5 labeled (cat. no. CT165).
References list
- Immunogenicity and safety of a DNA prime/adenovirus boost vaccine against rhesus CEA in nonhuman primates.
- White monkey syndrome in infant baboons (Papio species).
- Expression of CD154 by a simian immunodeficiency virus vector induces only transitory changes in rhesus macaques.
- Comparative analysis of inflammatory infiltrates in collagen-induced arthritis, kidney graft rejection and delayed-type hypersensitivity in non-human primates.
- Bortezomib can suppress activation of rapamycin-resistant memory T cells without affecting regulatory T-cell viability in non-human primates.
- Polymorphism for RhT3, a CD3-like cell surface antigen, expressed on rhesus monkey T lymphocytes.
- Safety of modified vaccinia virus Ankara (MVA) in immune-suppressed macaques.
- Preclinical studies of allograft tolerance in rhesus monkeys: a novel anti-CD3-immunotoxin given peritransplant with donor bone marrow induces operational tolerance to kidney allografts.