Catalogue Number
CT101
Description
mAb anti-monkey IFN-γ (clone MD-1) - 0.5 mg
Price
€ 305.00
Characteristics
clone MD-1
specificity
- Rhesus macaque
- Cynomolgus monkey
- Pig-tailed macaque
- Japanese macaque
- Baboon
- African green monkey
Summary
The neutralizing monoclonal antibody to monkey IFN-γ (clone MD-1) was first described in 1985. The MD-1 antibody can be used in a sandwich ELISA and in ELISPOT assays (Aurisicchio L. et al. 2007, Koopman G. et al. 2008, Mäkitalo B. et al. 2002 and van der Meide P.H. et al. 1995). Further, the antibody has been descriped in immunohistochemical staining of frozen tissues of marmosets (Villoslada P. et al. 2000) and in intracellular flow cytometric analysis (Hamann D. et al. 1996). The MD-1 antibody has been reported to cross react with rhesus macaque, pig-tailed macaque, cynomogus monkey, baboon and African green monkey IFN-γ and can be used in Luminex systems (Giavedoni L.D. 2005).
References list
- Immunogenicity and safety of a DNA prime/adenovirus boost vaccine against rhesus CEA in nonhuman primates.
- Increased, Durable B-Cell and ADCC Responses Associated with T-Helper Cell Responses to HIV-1 Envelope in Macaques Vaccinated with gp140 Occluded at the CD4 Receptor Binding Site.
- Simultaneous detection of multiple cytokines and chemokines from nonhuman primates using luminex technology.
- CD30 expression does not discriminate between human Th1- and Th2-type T cells.
- Immunization with apoptotic pseudovirus transduced cells induces both cellular and humoral responses: a proof of concept study in macaques.
- Immune-response profiles induced by human immunodeficiency virus type 1 vaccine DNA, protein or mixed-modality immunization: increased protection from pathogenic simian-human immunodeficiency virus viraemia with protein/DNA combination.
- ELISpot and ELISA analysis of spontaneous, mitogen-induced and antigen-specific cytokine production in cynomolgus and rhesus macaques.
- Pre-clinical evaluation of the malaria vaccine candidate P. falciparum MSP1(42) formulated with novel adjuvants or with alum.
- Monoclonal antibodies to human immune interferon and their use in a sensitive solid-phase ELISA.
- Enumeration of lymphokine-secreting cells as a quantitative measure for cellular immune responses in rhesus macaques.
- Genetic imprint of vaccination on simian/human immunodeficiency virus type 1 transmitted viral genomes in rhesus macaques.
- Human nerve growth factor protects common marmosets against autoimmune encephalomyelitis by switching the balance of T helper cell type 1 and 2 cytokines within the central nervous system.