Catalogue Number
CT035
Description
mAb anti-rat IFN-γ biotin (DB-1) - 0.5 mg
Price
€ 405.00
Characteristics
clone DB-1 (biotin)
Summary
The monoclonal antibody to rat IFN-γ (clone DB-1) was first described in 1989. It has shown to neutralize both natural and recombinant rat IFN-γ and mouse IFN-γ in vivo and in vitro. In a Western Blot the antibody reacts with the 14 kDa and 18 kDa polypeptides present in natural rat IFN-γ (van der Meide P.H. et al. 1989). The biotinyated DB-1 antibody is highly effective as detector antibody in both sandwich ELISA and ELISPOT assays using DB-12 (cat no. CT052) as coating antibody. Further, the DB-1 antibody can be used for immunohistochemical staining of frozen tissues (Aguilar Torrentera F. et al. 2002). Other available formats: unconjugated (cat. no. CT032) and FITC labeled (cat. no. CT034).
References list
- Endogenous interleukin-12 is critical for controlling the late but not the early stage of Leishmania mexicana infection in C57BL/6 mice.
- Isolation and characterization of monoclonal antibodies directed to rat interferon-gamma.
- The purification and characterization of rat gamma interferon by use of two monoclonal antibodies.