| Year | Reference |
|---|---|
|
2012
|
Investigation into the anti-inflammatory and antigranuloma activity of Colchicum luteum Baker in experimental models.
Inflammation
2012 Jun;35: 881-8
|
Abstract
The present study evaluates the anti-inflammatory and antigranuloma activity of CLHE in experimental models, viz. carrageenan-induced paw edema, subcutaneous cotton pellet implantation-induced granuloma formation, and complete Freund's adjuvant-induced stimulation of peritoneal macrophages in rats. Serum TNF-alpha, IL-6, and IL-1 beta levels were estimated as markers for global effects of inflammation. TNF-R1 protein expression was estimated in stimulated peritoneal macrophages. There was a significant reduction (P
Original publication