Reference Database

YearReference
1993
Elevated levels of T cell activation antigen CD27 and increased interleukin-4 production in human lymphatic filariasis.
Yazdanbakhsh, M
Sartono, E
Kruize, Y C
Kurniawan, A
van der Pouw-Kraan, T
van der Meide, P H
Selkirk, M E
Partono, F
Hintzen, R Q
van Lier, R A
European journal of immunology 1993 Dec;23: 3312-7
Abstract

To assess the immunological changes occurring during filarial infection with or without elephantiasis, 145 patients in different clinical groups from an endemic area in Indonesia were compared with respect to plasma levels of both soluble CD25 (sCD25) and sCD27; interleukin-4 (IL-4) and interferon-gamma release by peripheral blood mononuclear cells was also measured in a smaller subset of individuals. Levels of sCD27 were significantly elevated in elephantiasis and microfilaremic patients compared with endemic normals (p

Forward to a friend