Catalogue Number
CT050
Description
mAb anti-rat IFN-γ (clone DB-10) - 0.5 mg
Price
€ 222.00
Characteristics
clone DB-10
Summary
The mouse anti-rat IFN-γ monoclonal antibody (clone DB-10) is of the IgG1 substype. The DB-10 antibody has shown not to bind with rodent IFN-α1 and -β or to mouse or human IFN-γ and possesses very low neutralizing activity. In Western blot analysis the DB-10 antibody reacts with the 14 kDa and 18 kDa polypeptides present in rat IFN-γ (van der Meide P.H. et al. 1989). Further, the DB-10 antibody is effective in ELISA systems and is applicable in immunohistochemistry (Nennesmo I. et al. 1989 and Khoury S.J. et al. 1992).
References list
- Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4, and prostaglandin E expression in the brain.
- Interferon-gamma-like immunoreactivity and T-cell marker expression in rat skeletal muscle fibres.
- Isolation and characterization of monoclonal antibodies directed to rat interferon-gamma.