Rec. rat IFN-α1 (Sf9 cell-derived)

Catalogue Number

CT048

Description

Rec. rat IFN-α1 (Sf9 cell-derived) - 1 µg (1x10E5 U)

Price

€ 210.00

Characteristics

Insect cell-derived

Summary

Recombinant rat IFN-α1 produced by Sf9 cells using baculovirus. IFN-α is a type I interferon which is a key element in the mammalian first-line innate immune response. It functions in anti-viral, anti-proliferative and immunomodulatory activities and inhibits growth-promoting cytokines, induces apoptosis and inhibits cell proliferation.

Documentation

References list

Structure and expression in Escherichia coli of a cloned rat interferon-alpha gene.
Dijkema, R, et al. Nucleic Acids Res. 1984 Jan 25;12: 1227-42
Experimental Neuromyelitis Optica Induces a Type I Interferon Signature in the Spinal Cord.
Oji, Satoru, et al. PLoS ONE 2016;11: e0151244
The rat serum albumin gene: analysis of cloned sequences.
Sargent, T D, et al. Proc. Natl. Acad. Sci. U.S.A. 1979 Jul;76: 3256-60
Elevation in type I interferons inhibits HCN1 and slows cortical neuronal oscillations.
Stadler, Konstantin, et al. Cereb. Cortex 2014 Jan;24: 199-210
Cloning, expression, and purification of rat IFN-alpha 1.
van der Meide, P H, et al. Meth. Enzymol. 1986;119: 441-53