SDS-PAGE of purified recombinant rat IFN-beta.
Catalogue Number
CT044
Description
Rec. rat IFN-β (CHO-derived) - 150 µg (1x10E7 U)
Price
€ 762.00
Characteristics
CHO-derived
Summary
Recombinant rat IFN-beta produced by CHO cells. IFN-beta is a type I interferon which is a key element in the mammalian first-line innate immune response. It functions in anti-viral, anti-parasitic and anti-proliferative activities and it has shown to be of direct influence on the neuronal functioning.
References list
- Interferon-beta modulates protein synthesis in the central nervous system.
- Interferon-β attenuates lung inflammation following experimental subarachnoid hemorrhage.
- Neuromodulation by a cytokine: interferon-beta differentially augments neocortical neuronal activity and excitability.
- Interferon-beta fails to protect in a model of transient focal stroke.
- Experimental Neuromyelitis Optica Induces a Type I Interferon Signature in the Spinal Cord.
- Protein kinase C activation mediates interferon-β-induced neuronal excitability changes in neocortical pyramidal neurons.
- The length of treatment determines whether IFN-beta prevents or aggravates experimental autoimmune encephalomyelitis in Lewis rats.
- Elevation in type I interferons inhibits HCN1 and slows cortical neuronal oscillations.
- Effect of interferon-β on neuroinflammation, brain injury and neurological outcome after experimental subarachnoid hemorrhage.